Nutrient Database

Vitamin B7 (Biotin)

vitamin

Approved

General information about nutrients. No diagnosis, no medical advice. If you take medication, are pregnant or have a medical condition, talk to your doctor before taking supplements.

Fasting safe

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Overview

Water-soluble B vitamin and cofactor for carboxylase enzymes. Biotin contributes to the maintenance of normal hair. Biotin contributes to the maintenance of normal skin.

Interactions

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Biotin activation requires Mg

Biotin-dependent carboxylases (acetyl-CoA carboxylase, pyruvate carboxylase) require Mg2+ as a cofactor for ATP binding in the carboxylation reaction.

Top 5 food sources

Egg yolkslivernutssalmonsweet potatoes

Expert opinions

Dr. Strunz

Strunz treats Biotin (B7) as a cofactor for five key carboxylase enzymes that drive gluconeogenesis, fatty acid synthesis, and branched-chain amino acid catabolism. He uses 2.5 to 5 mg (2,500 to 5,000 mcg) as part of a B-complex because biotin shares an SMVT transporter with pantothenate and lipoic acid, and imbalanced mega-dosing suppresses uptake of the others. Important clinical caution: supplemental biotin above 5 mg for 8+ hours can distort troponin, TSH, and T4 immunoassays and mask heart-attack diagnosis, so he pauses biotin 48 to 72 h before blood draws.

Recommended dose: 2.5–5 mg

Source: Dr. Strunz

Expert profiles summarise publicly available statements. The named people do not cooperate with Stackwell and have not authorised these summaries. Not medical advice.

Expert consensus: Strong

No established UL. Very safe even at high doses. Can interfere with lab tests.