Pterostilbene
antioxidant
ApprovedGeneral information about nutrients. No diagnosis, no medical advice. If you take medication, are pregnant or have a medical condition, talk to your doctor before taking supplements.
Overview
Methylated form of resveratrol with superior bioavailability. Found in blueberries.
Research status
More bioavailable analog of resveratrol with 4x better absorption. Studied mainly in laboratory models such as yeast, with little human data so far.
Top 5 food sources
Expert opinions
Dr. David Sinclair
Sinclair describes pterostilbene as resveratrol's dimethylated blueberry analog. Its two methoxy groups make it about 80% orally bioavailable versus about 20% for resveratrol and extend its plasma half-life from about 2 h to about 7 h. Typical dose: 50 to 250 mg/day, often paired with NMN. He notes that the Dellinger 2014 human trial showed pterostilbene can raise LDL-C at higher doses, so lipid panels must be monitored.
Source: Dr. Sinclair Protocol
Expert profiles summarise publicly available statements. The named people do not cooperate with Stackwell and have not authorised these summaries. Not medical advice.
Better absorbed than resveratrol. Less clinical data but promising pharmacokinetics.