Quercetin
antioxidant
ApprovedGeneral information about nutrients. No diagnosis, no medical advice. If you take medication, are pregnant or have a medical condition, talk to your doctor before taking supplements.
Overview
Flavonoid found in onions, apples, and berries.
Interactions
Vitamin C regenerates oxidized quercetin and inhibits its oxidative degradation. Quercetin in turn recycles oxidized vitamin C (DHA to ascorbate), creating a synergistic antioxidant loop.
Bromelain's proteolytic enzymes enhance intestinal permeability for quercetin and reduce its glycoside hydrolysis, improving the absorption of this otherwise poorly bioavailable flavonoid.
Research status
Studied as a senolytic compound targeting senescent cells.
Top 5 food sources
Expert opinions
Dr. David Sinclair
Sinclair takes quercetin in periodic cycles, pulsed at about 500 mg daily for 2 to 3 consecutive days every few weeks rather than continuously. He uses the more bioavailable quercetin phytosome (Quercefit) with fat to overcome quercetin's notoriously poor absorption.
Recommended dose: 500 mg
Source: Dr. Sinclair Protocol
Expert profiles summarise publicly available statements. The named people do not cooperate with Stackwell and have not authorised these summaries. Not medical advice.
Studied in preclinical models and human pilot studies.